Cytochrome c specifically induces non-bilayer structures in cardiolipin-containing model membranes.
نویسندگان
چکیده
(1) The effect of cytochrome c addition on the phospholipid structure of liposomes composed of cardiolipin, phosphatidylserine, phosphatidylglycerol, phosphatidylcholine or phosphatidylethanolamine in a pure form or in mixtures was investigated by 31P-NMR and freeze-fracture techniques. (2) Cytochrome c specifically induces the hexagonal Hii phase and possibly an inverted micellar structure of part of the phospholipids in cardiolipin-containing model membranes. (3) These results are compared with the effect of Ca2+ on cardiolipin and are discussed in relation to the structure and function of the inner mitochondrial membrane.
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عنوان ژورنال:
- Biochimica et biophysica acta
دوره 602 3 شماره
صفحات -
تاریخ انتشار 1980